Enhanced Delivery of the RAPTA-C Macromolecular Chemotherapeutic by Conjugation to Degradable Polymeric Micelles
Author:
Affiliation:
1. Centre for Advanced Macromolecular Design, University of New South Wales, Sydney, New South Wales 2052, Australia
2. Cooperative Research Centre (CRC) for Polymers, 8 Redwood Drive, Notting Hill, Victoria 3618, Australia
Publisher
American Chemical Society (ACS)
Subject
Materials Chemistry,Polymers and Plastics,Biomaterials,Bioengineering
Link
https://pubs.acs.org/doi/pdf/10.1021/bm4013919
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1. [Ru(η6-p-cymene)Cl2(pta)] (pta = 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane): a water soluble compound that exhibits pH dependent DNA binding providing selectivity for diseased cells
2. A Ruthenium Antimetastasis Agent Forms Specific Histone Protein Adducts in the Nucleosome Core
3. In Vitro and in Vivo Evaluation of Ruthenium(II)−Arene PTA Complexes
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