Design and Synthesis of Skeletal Analogues of Gambierol: Attenuation of Amyloid-β and Tau Pathology with Voltage-Gated Potassium Channel and N-Methyl-d-aspartate Receptor Implications-Reference-Cited by-同舟云学术

Design and Synthesis of Skeletal Analogues of Gambierol: Attenuation of Amyloid-β and Tau Pathology with Voltage-Gated Potassium Channel and N-Methyl-d-aspartate Receptor Implications

Published:2012-04-18 Issue:17 Volume:134 Page:7467-7479
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Alonso Eva¹,Fuwa Haruhiko²,Vale Carmen¹,Suga Yuto²,Goto Tomomi²,Konno Yu²,Sasaki Makoto²,LaFerla Frank M.³,Vieytes Mercedes R.⁴,Giménez-Llort Lydia⁵,Botana Luis M.¹

Affiliation:

1. Departamento de Farmacología, Facultad de Veterinaria, Universidad de Santiago de Compostela, Lugo, Spain

2. Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan

3. Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697, United States

4. Departamento de Fisiología, Facultad de Veterinaria, Universidad de Santiago de Compostela, 27003 Lugo, Spain

5. Departamento de Psiquiatría y Medicina Legal, Instituto de Neurociencias, Universidad Autonoma de Barcelona, 08193 Bellaterra, Spain

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja300565t

Reference97 articles.

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2. Marine toxins

3. The structure elucidation and biological activities of high molecular weight algal toxins: maitotoxin, prymnesins and zooxanthellatoxins (1993 to 1999)

4. Pathological effects on mice by gambierol, possibly one of the ciguatera toxins

5. Gambierol: a new toxic polyether compound isolated from the marine dinoflagellate Gambierdiscus toxicus

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