Sustained Release GLP-1 Agonist PT320 Delays Disease Progression in a Mouse Model of Parkinson’s Disease

Author:

Wang Vicki1,Kuo Tung-Tai2,Huang Eagle Yi-Kung3,Ma Kuo-Hsing4,Chou Yu-Ching5,Fu Zhao-Yang6,Lai Li-Wen7,Jung Jin8,Choi Hoi-II8,Choi Doo-Sup9ORCID,Li Yazhou10,Olson Lars11,Greig Nigel H.10,Hoffer Barry J.12,Chen Yuan-Hao6ORCID

Affiliation:

1. Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei 11490, Taiwan

2. Graduate Institute of Computer and Communication Engineering, National Taipei University of Technology, Taipei 10608, Taiwan

3. Department of Pharmacology, National Defense Medical Center, Taipei 11490, Taiwan

4. Graduate Institute of Biology and Anatomy, National Defense Medical Center, Taipei, 11490, Taiwan

5. National Defense Medical Center School of Public Health, Min-Chuan East Road, Sec. 6, Nei-Hu District, Taipei City, 114, Taiwan

6. Department of Neurological Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan

7. Graduate Pharmacology, National Defense Medical Center, Taipei 11490, Taiwan

8. Peptron, Inc., Yuseong-gu, Daejeon 34054, Republic of Korea

9. Departments of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine & Science, Rochester, Minnesota 55905-0001, United States

10. Drug Design & Development Section, Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224-6825, United States

11. Department of Neuroscience, Karolinska Institute, Stockholm 171 77, Sweden

12. Department of Neurosurgery, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106-4915, United States

Funder

U.S. Department of Health and Human Services

Vetenskapsr??det

National Research Foundation of Korea

Hj??rnfonden

Ministry of Trade, Industry and Energy

Ministry of Science and Technology, Taiwan

National Defense Medical Center, Taiwan

Tri-Service General Hospital, Taiwan

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

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