Development and Preclinical Evaluation of a Copper-64-Labeled Antibody Targeting Glycine-Alanine Dipeptides for PET Imaging of C9orf72-Associated Amyotrophic Lateral Sclerosis/Frontotemporal Dementia-Reference-Cited by-同舟云学术

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Development and Preclinical Evaluation of a Copper-64-Labeled Antibody Targeting Glycine-Alanine Dipeptides for PET Imaging of C9orf72-Associated Amyotrophic Lateral Sclerosis/Frontotemporal Dementia

Published:2024-04-25 Issue:5 Volume:7 Page:1404-1414
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Shojaei Monireh¹,Zhou Qihui²,Palumbo Giovanna¹,Schaefer Rebecca¹,Kaskinoro Janne³,Vehmaan-Kreula Pirjo³,Bartenstein Peter¹⁴,Brendel Matthias¹²⁴,Edbauer Dieter²⁴,Lindner Simon¹^ORCID

Affiliation:

1. Department of Nuclear Medicine, University Hospital, LMU Munich, 81377 Munich, Germany

2. German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany

3. Orion Corporation Orion Pharma, 02200 Espoo, Finland

4. Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany

Funder

Deutsche Forschungsgemeinschaft

HORIZON EUROPE Framework Programme

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.4c00037

Reference39 articles.

1. Frontotemporal Dementia – Current Concepts

2. Inflammation in ALS/FTD pathogenesis

3. Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis

4. The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS

5. Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

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