Stabilization of Cyclin-Dependent Kinase 4 by Methionyl-tRNA Synthetase in p16INK4a-Negative Cancer

Author:

Kwon Nam Hoon12,Lee Jin Young1,Ryu Ye-lim1,Kim Chanhee1,Kong Jiwon1,Oh Seongeun1,Kang Beom Sik3,Ahn Hye Won1,Ahn Sung Gwe4,Jeong Joon4,Kim Hoi Kyoung1,Kim Jong Hyun1,Han Dae Young1,Park Min Chul1,Kim Doyeun1,Takase Ryuichi5,Masuda Isao5,Hou Ya-Ming5,Jang Sung Ill6,Chang Yoon Soo6,Lee Dong Ki6,Kim Youngeun1,Wang Ming-Wei7,Basappa 8ORCID,Kim Sunghoon12ORCID

Affiliation:

1. Medicinal Bioconvergence Research Center, Seoul National University, Suwon, 16229, Korea

2. Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, Korea

3. School of Life Science and Biotechnology, Kyungpook National University, Daegu, 41566, Korea

4. Breast Cancer Center, Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, 03722, Korea

5. Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, United States;

6. Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, 03722, Korea

7. The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China

8. Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Palace Road, Bangalore, 560 001, India

Funder

Ministry of Health and Welfare

National Research Foundation of Korea

Gyeonggi Research Development Program

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

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