Lipophilicity Determines Routes of Uptake and Clearance, and Toxicity of an Alpha-Particle-Emitting Peptide Receptor Radiotherapy-Reference-Cited by-同舟云学术

Lipophilicity Determines Routes of Uptake and Clearance, and Toxicity of an Alpha-Particle-Emitting Peptide Receptor Radiotherapy

Published:2021-03-12 Issue:2 Volume:4 Page:953-965
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Tafreshi Narges K.¹^ORCID,Kil HyunJoo²³,Pandya Darpan N.⁴,Tichacek Christopher J.⁵^ORCID,Doligalski Michael L.¹^ORCID,Budzevich Mikalai M.,Delva Nella C.¹,Langsen Michael L.¹^ORCID,Vallas John A.¹,Boulware David C.,Engelman Robert W.,Gage Kenneth L.,Moros Eduardo G.¹⁵,Wadas Thaddeus J⁴^ORCID,McLaughlin Mark L.²³,Morse David L.¹⁵

Affiliation:

1. Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, United States

2. Department of Pharmaceutical Sciences, West Virginia University, Health Sciences Center, Morgantown, West Virginia 26506, United States

3. Modulation Therapeutics, Inc., Morgantown, West Virginia 26506, United States

4. Department of Radiology, University of Iowa Health Care, Iowa City, Iowa 52242, United States

5. Department of Physics, University of South Florida, Tampa, Florida 33612, United States

Funder

Moffitt Radiology Pilot Award

NIH/NCI SBIR Phase 1 Contract to Modulation Therapeutics

Melanoma Research Alliance Team Science Award

H. Lee Moffitt Cancer Center & Research Institute an NCI designated Comprehensive Cancer Center

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.1c00035

Reference42 articles.

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