Pharmacological Analysis of NLRP3 Inflammasome Inhibitor Sodium [(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl][(1-methyl-1<i>H</i>-pyrazol-4-yl)({[(2<i>S</i>)-oxolan-2-yl]methyl})sulfamoyl]azanide in Cellular and Mouse Models of Inflammation Provides a Translational Framework-Reference-Cited by-同舟云学术

Pharmacological Analysis of NLRP3 Inflammasome Inhibitor Sodium [(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl][(1-methyl-1H-pyrazol-4-yl)({[(2S)-oxolan-2-yl]methyl})sulfamoyl]azanide in Cellular and Mouse Models of Inflammation Provides a Translational Framework

Published:2024-04-18 Issue:5 Volume:7 Page:1438-1456
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Doedens John R.¹,Smolak Pamela¹,Nguyen MyTrang²,Wescott Heather¹,Diamond Christine¹,Schooley Ken¹,Billinton Andy³,Harrison David³^ORCID,Koller Beverly H.²,Watt Alan P.³,Gabel Christopher A.¹^ORCID

Affiliation:

1. NodThera, Inc., Seattle, Washington 98103, United States

2. Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States

3. NodThera Ltd, Little Chesterford, Saffron Walden, Essex CB10 1XL, U.K.

Funder

NodThera

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.4c00061

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