An Optimized Microscale Thermophoresis Method for High-Throughput Screening of DNA Methyltransferase 2 Ligands
Author:
Affiliation:
1. Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz Staudinger Weg 5, D-55128 Mainz, Germany
Funder
Deutsche Forschungsgemeinschaft
Volkswagen Foundation
Publisher
American Chemical Society (ACS)
Subject
Pharmacology (medical),Pharmacology
Link
https://pubs.acs.org/doi/pdf/10.1021/acsptsci.2c00175
Reference43 articles.
1. Cloning and analysis of a novel human putative DNA methyltransferase
2. Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA
3. Methylation of tRNA Asp by the DNA Methyltransferase Homolog Dnmt2
4. RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage
5. RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis
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