Bruceine B Displays Potent Antimyeloma Activity by Inducing the Degradation of the Transcription Factor c-Maf-Reference-Cited by-同舟云学术

Bruceine B Displays Potent Antimyeloma Activity by Inducing the Degradation of the Transcription Factor c-Maf

Published:2023-12-05 Issue:1 Volume:7 Page:176-185
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Li Hongyue¹²,Zhu Xiaoting¹²,Sun Ziying²,Wang Qi¹,Song Shaojiang³,Xu Yujia²,He Guisong⁴,Mao Xinliang¹²^ORCID

Affiliation:

1. Institute of Clinical Pharmacology, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510006, China

2. Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou 511436, P. R. China

3. Department of Natural Medicinal Chemistry, Shenyang Pharmaceutical University, Shenyang 110016, China

4. Department of Orthopaedics, the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou 510260, P. R. China

Funder

National Key Research and Development Program of China

Guangzhou Medical University

Department of Education of Guangdong Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.3c00222

Reference31 articles.

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3. MAF protein mediates innate resistance to proteasome inhibition therapy in multiple myeloma

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5. Targeting the oncogenic transcription factor c-Maf for the treatment of multiple myeloma

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