Distinguishing Pharmacokinetics of Marketed Nanomedicine Formulations Using a Stable Isotope Tracer Assay

Author:

Skoczen Sarah L.1,Snapp Kelsie S.1,Crist Rachael M.1,Kozak Darby2,Jiang Xiaohui2,Liu Hao2,Stern Stephan T.1ORCID

Affiliation:

1. Nanotechnology Characterization Laboratory, Cancer Research Technology Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, Frederick, Maryland 21702, United States

2. Office of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland 20993, United States

Funder

National Cancer Institute

U.S. Food and Drug Administration

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

Reference34 articles.

1. European Medicines Agency (EMA), Committee for Medicinal Products for Human Use (CHMP) (2013) Reflection paper on the data requirements for intravenous liposomal products developed with reference to an innovator liposomal product, European Medicines Agency.

2. Food and Drug Administration (FDA), Office of Generic Drugs (2012) Draft guidance on paclitaxel, Food and Drug Administration.

3. European Medicines Agency (EMA), Committee for Medicinal Products for Human Use (CHMP) (2013) Joint MHLW/EMA reflection paper on the development of block copolymer micelle medicinal products, European Medicines Agency.

4. Food and Drug Administration (FDA), Office of Generic Drugs (2013) Draft guidance on doxorubicin hydrochloride, Food and Drug Administration.

5. Food and Drug Administration (FDA) (2014) Draft guidance on daunorubicin citrate, Food and Drug Administration

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