Analysis of the Selective Antagonist SAFit2 as a Chemical Probe for the FK506-Binding Protein 51-Reference-Cited by-同舟云学术

Analysis of the Selective Antagonist SAFit2 as a Chemical Probe for the FK506-Binding Protein 51

Published:2023-02-14 Issue:3 Volume:6 Page:361-371
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Buffa Vanessa¹^ORCID,Knaup Fabian H.¹,Heymann Tim¹,Springer Margherita²,Schmidt Mathias V.²,Hausch Felix¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, Clemens-Schöpf-Institute, Technical University Darmstadt, Alarich-Weiss Straße 4, 64287 Darmstadt, Germany

2. Research Group Neurobiology of Stress Resilience, Max Planck Institute of Psychiatry, 80804 Munich, Germany

Funder

Bundesministerium f??r Bildung und Forschung

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.2c00234

Reference90 articles.

1. The Many Faces of FKBP51

2. FKBP Ligands—Where We Are and Where to Go?

3. Selective inhibitors of the FK506-binding protein 51 by induced fit

4. Squirrel Monkey Immunophilin FKBP51 Is a Potent Inhibitor of Glucocorticoid Receptor Binding1

5. Biological Actions of the Hsp90-binding Immunophilins FKBP51 and FKBP52

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1. Structure‐Based Design of Ultrapotent Tricyclic Ligands for FK506‐Binding Proteins;Chemistry – A European Journal;2024-07-25

2. 1,4‐Pyrazolyl‐Containing SAFit‐Analogues are Selective FKBP51 Inhibitors With Improved Ligand Efficiency and Drug‐Like Profile;ChemMedChem;2024-07-08

3. The Role of FKBPs in Complex Disorders: Neuropsychiatric Diseases, Cancer, and Type 2 Diabetes Mellitus;Cells;2024-05-08

4. FKBP5 regulates trophoblast-macrophage crosstalk in recurrent spontaneous abortion through PI3K/AKT and NF-κB signaling pathways;Free Radical Biology and Medicine;2023-11

5. SAFit2 ameliorates paclitaxel-induced neuropathic pain by reducing spinal gliosis and elevating pro-resolving lipid mediators;Journal of Neuroinflammation;2023-06-24