In Vitro Characterization of 6-Methyl-3-(2-nitro-1-(thiophen-2-yl)ethyl)-2-phenyl-1<i>H</i>-indole (ZCZ011) at the Type 1 Cannabinoid Receptor: Allosteric Agonist or Allosteric Modulator?-Reference-Cited by-同舟云学术

In Vitro Characterization of 6-Methyl-3-(2-nitro-1-(thiophen-2-yl)ethyl)-2-phenyl-1H-indole (ZCZ011) at the Type 1 Cannabinoid Receptor: Allosteric Agonist or Allosteric Modulator?

Published:2022-11-22 Issue:12 Volume:5 Page:1279-1291
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Green Hayley M.¹,Finlay David B.¹^ORCID,Ross Ruth A.²,Greig Iain R.³,Duffull Stephen B.⁴,Glass Michelle¹^ORCID

Affiliation:

1. Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin9054, New Zealand

2. Department of Pharmacology and Toxicology, Faculty of Medicine, University of Toronto, TorontoM5S 1A8, Canada

3. School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, AberdeenAB24 3FX, U.K.

4. Otago Pharmacometrics Group, School of Pharmacy, University of Otago, Dunedin9016, New Zealand

Funder

University of Otago

School of Biomedical Sciences, University of Otago

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.2c00160

Reference46 articles.

1. Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish

2. Structure of a cannabinoid receptor and functional expression of the cloned cDNA

3. Molecular characterization of a peripheral receptor for cannabinoids

4. Cannabinoid Receptors: An Update on Cell Signaling, Pathophysiological Roles and Therapeutic Opportunities in Neurological, Cardiovascular, and Inflammatory Diseases

5. The diverse CB1and CB2receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin

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