Identification of PDCD2 as a Candidate Target of Andrographolide That Arrests the Tumor Cell Cycle by Human Proteome-Scale Screening-Reference-Cited by-同舟云学术

Identification of PDCD2 as a Candidate Target of Andrographolide That Arrests the Tumor Cell Cycle by Human Proteome-Scale Screening

Published:2022-06-24 Issue:7 Volume:5 Page:479-490
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Wang Lei¹,Li Caifeng¹,Chen Peng²^ORCID,Liu Chunyuan³,Cui Zhao⁴,Deng Shiwen¹,Yang Hongjun⁵

Affiliation:

1. Beijing Key Laboratory of Traditional Chinese Medicine Basic Research on Prevention and Treatment for Major Diseases, Experimental Research Center, China Academy of Chinese Medical Sciences, Beijing 100700, China

2. Robot intelligence laboratory, Experimental Research Center, China Academy of Chinese Medical Sciences, Dongcheng District, Beijing 100700, China

3. Department of Surgery, Yantai Affiliated Hospital of Binzhou Medical University, Yantai 264100, China

4. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China

5. Experimental Research Center, China Academy of Chinese Medical Sciences, Dongcheng District, Beijing 100700, China

Funder

Chinese Research Academy of Environmental Sciences

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.2c00092

Reference38 articles.

1. How many drug targets are there?

2. The drug–target residence time model: a 10-year retrospective

3. Drug Target Identification Using Side-Effect Similarity

4. Phenotypic screening in cancer drug discovery — past, present and future

5. Target identification and mechanism of action in chemical biology and drug discovery

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