Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein–Protein Interaction Inhibitors-Reference-Cited by-同舟云学术

Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein–Protein Interaction Inhibitors

Published:2023-10-09 Issue:11 Volume:6 Page:1651-1658
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Francisco Karol R.¹²,Bruystens Jessica³,Varricchio Carmine⁴^ORCID,McCurdy Sara⁵,Wu Jian³,Lopez-Ramirez Miguel A.³⁵,Ginsberg Mark⁵,Caffrey Conor R.⁶,Brancale Andrea⁴⁷^ORCID,Gingras Alexandre R.⁵,Hixon Mark S.⁸,Ballatore Carlo²^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States

2. Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States

3. Department of Pharmacology, University of California, San Diego, California 92161, United States

4. School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff CF103NB, U.K.

5. Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States

6. Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States

7. Vysoká Sk̆ola Chemicko-Technologická v Praze, Department of Organic ChemistryTechnická 5, Prague 16628, Czech Republic

8. Mark S. Hixon Consulting LLC, 11273Spitfire Road, San Diegom California 92126, United States

Funder

University of California, San Diego

National Heart, Lung, and Blood Institute

University of California

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

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