Comparison of the Tissue Distribution of a Long-Circulating Glucagon-like Peptide-1 Agonist Determined by Positron Emission Tomography and Quantitative Whole-Body Autoradiography-Reference-Cited by-同舟云学术

Comparison of the Tissue Distribution of a Long-Circulating Glucagon-like Peptide-1 Agonist Determined by Positron Emission Tomography and Quantitative Whole-Body Autoradiography

Published:2022-06-30 Issue:8 Volume:5 Page:616-624
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Fernandes Eduardo Felipe Alves¹^ORCID,Wilbs Jonas²,Raavé Rene³,Jacobsen Christian Borch⁴^ORCID,Toftelund Hanne¹,Helleberg Hans¹,Boswinkel Milou³,Heskamp Sandra³^ORCID,Gustafsson Magnus Bernt Frederik²,Bjørnsdottir Inga¹

Affiliation:

1. Global Drug Discovery, Novo Nordisk A/S, Novo Nordisk Park 1, DK-2760 Måløv, Denmark

2. Global Research Technologies, Novo Nordisk A/S, Novo Nordisk Park 1, DK-2760 Måløv, Denmark

3. Radboudumc, Department of Medical Imaging − Nuclear Medicine, Radboud Institute for Molecular Life Sciences, 6500 HB Nijmegen, The Netherlands

4. Isotope Chemistry, CMC Development, Novo Nordisk A/S, Novo Nordisk Park 1, DK-2760 Måløv, Denmark

Funder

Horizon 2020 Framework Programme

European Federation of Pharmaceutical Industries and Associations

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.2c00075

Reference35 articles.

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2. Quantitative whole-body autoradiography: past, present and future

3. Use of Radioactive Compounds and Autoradiography to Determine Drug Tissue Distribution

4. Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies in Drug Development: Why, When, and How?

5. Positron emission tomography molecular imaging for drug development

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