Model-Informed Dose Selection for a Novel Human Immunoglobulin G4 Derived Monoclonal Antibody Targeting Proprotein Convertase Kwashiorkor Type 9: Insights from Population Pharmacokinetics–Pharmacodynamics and Systems Pharmacology

Author:

Peng Jinfu12ORCID,Huang Jie1,Tan Hongyi1,Kuang Yun1,Yang Guoping123ORCID,Huang Zhijun13

Affiliation:

1. Center for Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha 410013 Hunan, China

2. Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410031 Hunan, China

3. National Engineering Research Center of Personalized Diagnostic and Therapeutic Technology, Changsha 410008 Hunan, China

Funder

Natural Science Foundation of Hunan Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

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1. Progress in physiologically based pharmacokinetic-pharmacodynamic models of amino acids in humans;Current Opinion in Clinical Nutrition & Metabolic Care;2024-08-05

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