Synthesis of 5-[(Indol-2-on-3-yl)methyl]-2,2-dimethyl-1,3- dioxane-4,6-diones and Spirocyclopropyloxindole Derivatives. Potential Aldose Reductase Inhibitors-Reference-Cited by-同舟云学术

Synthesis of 5-[(Indol-2-on-3-yl)methyl]-2,2-dimethyl-1,3- dioxane-4,6-diones and Spirocyclopropyloxindole Derivatives. Potential Aldose Reductase Inhibitors

Published:1999-02-01 Issue:4 Volume:64 Page:1369-1371
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Rajeswaran Walajapet G.¹,Labroo Rita B.¹,Cohen Louis A.¹,King Michael M.²

Affiliation:

1. Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, Maryland 20892

2. Department of Chemistry, The George Washington University, Washington, D.C. 20052

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo981673r

Reference16 articles.

1. Cameron, N. E.; Cotter, M. A.; Basso, M.; Hohman, T. C.Diabetologia1997,40, 271.

2. Aldose reductase inhibitors and their potential for the treatment of diabetic complications

3. Synthesis and biological activities of aldose reductase inhibitors bearing acyl benzenesulfonamides as carboxylic acid surrogates

4. Structure-based design of an inhibitor modeled at the substrate active site of aldose reductase

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