Structural and Thermodynamic Basis of the Enhanced Interaction between Kinesin Spindle Protein Eg5 and STLC-type Inhibitors
Author:
Affiliation:
1. Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan
Funder
Japan Society for the Promotion of Science
Pharma Valley Center
Publisher
American Chemical Society (ACS)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.acs.org/doi/pdf/10.1021/acsomega.8b00778
Reference48 articles.
1. Strategies in the Search for New Lead Compounds or Original Working Hypotheses
2. Reporting data from high-throughput screening of small-molecule libraries
3. CURRENT PROGRESS IN STRUCTURE-BASED RATIONAL DRUG DESIGN MARKS A NEW MINDSET IN DRUG DISCOVERY
4. Increasing the delivery of next generation therapeutics from high throughput screening libraries
5. Novel approach of fragment-based lead discovery applied to renin inhibitors
Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Binding patterns of inhibitors to different pockets of kinesin Eg5;Archives of Biochemistry and Biophysics;2024-06
2. RAB11A and RAB11B control mitotic spindle function in intestinal epithelial progenitor cells;EMBO reports;2023-07-10
3. Crystal structure of the motor domain of centromere‐associated protein E in complex with a non‐hydrolysable ATP analogue;FEBS Letters;2023-03-05
4. Various effects of two types of kinesin-5 inhibitors on mitosis and cell proliferation;Biochemical Pharmacology;2021-11
5. Kolaflavanone, a biflavonoid derived from medicinal plant Garcinia, is an inhibitor of mitotic kinesin Eg5;The Journal of Biochemistry;2021-07-15
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3