Synthesis and In Vitro α-Amylase and α-Glucosidase Dual Inhibitory Activities of 1,2,4-Triazole-Bearingbis-Hydrazone Derivatives and Their Molecular Docking Study

Author:

Khan Imran1,Rehman Wajid1ORCID,Rahim Fazal1,Hussain Rafaqat1,Khan Shoaib1,Rasheed Liaqat1,Alanazi Mohammed M.2,Alanazi Ashwag S.3,Abdellattif Magda H.4ORCID

Affiliation:

1. Department of Chemistry, Hazara University, Mansehra 21120, Pakistan

2. Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P. O. Box 2457, Riyadh 11451, Saudi Arabia

3. Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, P. O. Box 84428, Riyadh 11671, Saudi Arabia

4. Department of Chemistry, College of Sciences, Taif University, P. O. Box 11099, Taif 21944, Saudi Arabia

Funder

Princess Nourah Bint Abdulrahman University

King Saud University

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Reference52 articles.

1. Oral sustained release nystatin tablets for the treatment of oral candidiasis: formulation development and validation of UV spectrophotometric analytical methodology for content determination

2. Fall, J. A.; Holen, D. L.; Davis, B.; Krieg, T.; Koster, D.Subsistence harvests and uses of wild resources in Iliamna, Newhalen, Nondalton, Pedro Bay, and Port Alsworth, Alaska, Alaska Department of Fish and Game Division of SubsistenceTechnical Paper2006, p 302.

3. Postprandial hyperglycaemia and α-glucosidase inhibitors

4. Proteasome inhibitors: valuable new tools for cell biologists

5. beta-cell dysfunction and failure in type 2 diabetes: potential mechanisms.

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