Imidazopyridine Amides: Synthesis, Mycobacterium smegmatis CIII2CIV2 Supercomplex Binding, and In Vitro Antimycobacterial Activity

Author:

Abdelaziz Rana1,Di Trani Justin M2,Sahile Henok3,Mann Lea1,Richter Adrian1ORCID,Liu Zhongle4,Bueler Stephanie A.2,Cowen Leah E.4ORCID,Rubinstein John L.256ORCID,Imming Peter1ORCID

Affiliation:

1. Institut Für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle (Saale) 06120, Germany

2. Molecular Medicine Program, The Hospital for Sick Children, Toronto M5G 0A4, Canada

3. Departments of Medicine and Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver V6T 1Z3, Canada

4. Department of Molecular Genetics, The University of Toronto, Toronto M5G 0A4, Canada

5. Department of Medical Biophysics, The University of Toronto, Toronto M5G 0A4, Canada

6. Department of Biochemistry, The University of Toronto, Toronto M5G 0A4, Canada

Funder

Canadian Institutes of Health Research

Deutscher Akademischer Austauschdienst

Canada Research Chairs

Canadian Institute for Advanced Research

Precision Medicine Initiative

Stiftung f?r Kanada-Studien

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Reference49 articles.

1. Global Tuberculosis Report 2021. Geneva: World Health Organization; 2021. Licence: CC BY-NC-SA 3.0 IGO. Geneva, Switzerland.

2. United States; Department of Health and Human Services, C for D. C. and P. Tuberculosis (TB): Data and Statistics. https://www.cdc.gov/tb/statistics/tbcases.htm.

3. RKI. Report on the Epidemiology of Tuberculosis in Germany 2020 .

4. World Bank. Incidence of tuberculosis. https://data.worldbank.org/indicator/SH.TBS.INCD.

5. CELL BIOLOGY OF MYCOBACTERIUM TUBERCULOSIS PHAGOSOME

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