Discovery of Lonafarnib-Like Compounds: Pharmacophore Modeling and Molecular Dynamics Studies-Reference-Cited by-同舟云学术

Discovery of Lonafarnib-Like Compounds: Pharmacophore Modeling and Molecular Dynamics Studies

Published:2020-01-22 Issue:4 Volume:5 Page:1773-1781
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Rampogu Shailima¹,Baek Ayoung¹,Son Minky¹,Park Chanin¹,Yoon Sanghwa¹,Parate Shraddha¹,Lee Keun Woo¹^ORCID

Affiliation:

1. Division of Life Science, Division of Applied Life Science (BK21 Plus), Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Research Institute of Natural Science (RINS), Gyeongsang National University (GNU), 501 Jinju-daero, Jinju 52828, Republic of Korea

Funder

National Research Foundation of Korea

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acsomega.9b02263

Reference30 articles.

1. Hutchinson-Gilford progeria syndrome

2. Hutchinson-Gilford Progeria Syndrome: A premature aging disease caused by LMNA gene mutations

3. Progerin, the protein responsible for the Hutchinson-Gilford progeria syndrome, increases the unrepaired DNA damages following exposure to ionizing radiation

4. Progeria, the nucleolus and farnesyltransferase inhibitors

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