Microsecond Simulation of the Proteoglycan-like Region of Carbonic Anhydrase IX and Design of Chemical Inhibitors Targeting pH Homeostasis in Cancer Cells-Reference-Cited by-同舟云学术

Microsecond Simulation of the Proteoglycan-like Region of Carbonic Anhydrase IX and Design of Chemical Inhibitors Targeting pH Homeostasis in Cancer Cells

Published:2020-02-20 Issue:8 Volume:5 Page:4270-4281
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

John Arun¹²,Vetrivel Umashankar¹^ORCID,Sivashanmugam Muthukumaran¹,Natarajan Sulochana Konerirajapuram³

Affiliation:

1. Centre for Bioinformatics, Kamalnayan Bajaj Institute for Research in Vision and Ophthalmology, Vision Research Foundation, Sankara Nethralaya, Chennai 600 006, Tamil Nadu, India

2. School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, Tamil Nadu, India

3. R.S. Mehta Jain Department of Biochemistry and Cell Biology, Kamalnayan Bajaj Institute for Research in Vision and Ophthalmology, Vision Research Foundation, Sankara Nethralaya, Chennai 600 006, Tamil Nadu, India

Funder

Indian Council of Medical Research

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acsomega.9b04203

Reference96 articles.

1. Recent Developments in Targeting Carbonic Anhydrase IX for Cancer Therapeutics

2. Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

3. Structure and function of carbonic anhydrases