Small Molecule Screen Identifies Non-catalytic USP3 Chemical Handle-Reference-Cited by-同舟云学术

Small Molecule Screen Identifies Non-catalytic USP3 Chemical Handle

Published:2023-12-15 Issue:1 Volume:9 Page:917-924
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Mann Mandeep K.¹²,Wolf Esther³,Silva Madhushika¹,Kwak Haejin Angela¹²,Wilson Brian⁴,Bolotokova Albina¹,Wilson Derek J.³^ORCID,Harding Rachel J.¹²^ORCID,Schapira Matthieu¹²^ORCID

Affiliation:

1. Structural Genomics Consortium, University of Toronto, 101 College Street, MaRS South Tower, Suite 700, Toronto, Ontario M5G 1L7, Canada

2. Department of Pharmacology and Toxicology, University of Toronto, 1 King’s College Circle, Toronto, Ontario M5S 1A8, Canada

3. Department of Chemistry, York University, Toronto, Ontario M3J 1P3, Canada

4. Drug Discovery Program, Ontario Institute for Cancer Research, Toronto, Ontario M5G 0A3, Canada

Funder

Qu?bec Consortium for Drug Discovery

Peterborough K. M. Hunter Charitable Foundation

Natural Sciences and Engineering Research Council of Canada

Mitacs

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.3c07070

Reference36 articles.

1. Deubiquitinase-targeting chimeras for targeted protein stabilization

2. The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin

3. Zinc-finger UBPs: regulators of deubiquitylation

4. Solution Structure of the Ubp-M BUZ Domain, a Highly Specific Protein Module that Recognizes the C-terminal Tail of Free Ubiquitin

5. Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP