Design, Synthesis, Characterization, and Crystal Structure Studies of Nrf2 Modulators for Inhibiting Cancer Cell Growth In Vitro and In Vivo

Author:

Chikkegowda Prathima1,Pookunoth Baburajeev C.2,Bovilla Venugopal R.34,Veeresh Prashanthkumar M.34,Leihang Zonunsiami34,Thippeswamy Thippeswamy5,Padukudru Mahesh A.6,Hathur Basavanagowdappa45789,Kanchugarakoppal Rangappa S.10,Basappa 2ORCID,Madhunapantula SubbaRao V.311ORCID

Affiliation:

1. Department of Pharmacology, JSS Medical College, JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India

2. Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Mysore 570005, Karnataka, India

3. Department of Biochemistry (DST-FIST Supported Department), JSS Medical College, JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India

4. Center of Excellence in Molecular Biology and Regenerative Medicine (CEMR, DST-FIST Supported Center), JSS Medical College, JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India

5. Department of General Medicine, JSS Medical College and Hospital, JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India

6. Department of Respiratory Medicine, JSS Medical College, and Hospital, JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India

7. Faculty of Medicine, JSS Medical College and Hospital, JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India

8. JSS Medical College and Hospital, JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India

9. Special Interest Group in Patient Care Management, JSS Medical College and Hospital, JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India

10. Department of Studies in Chemistry, University of Mysore, Mysore 570005, Karnataka, India

11. Special Interest Group in Cancer Biology and Cancer Stem Cells (SIG-CBCSC), JSS Academy of Higher Education & Research, Mysore 570015, Karnataka, India

Funder

Indian Council of Medical Research

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

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