Synthesis of an Alleged Byproduct Precursor in Iodixanol Preparation
Author:
Affiliation:
1. Faculty of Science and Technology, Department of Mathematics and Natural Sciences, University of Stavanger, NO-4036 Stavanger, Norway
2. GE Healthcare AS, NO-4521 Lindesnes, Norway
Funder
GE Healthcare
University of Stavanger
Publisher
American Chemical Society (ACS)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.acs.org/doi/pdf/10.1021/acsomega.8b00411
Reference26 articles.
1. Formation of N,O-Acetals in the Production of X-ray Contrast Agents
2. Peng, Y.; Liu, F.; Zhang, X.; Zhong, Z. Method for preparing iodixanol and its synthetic intermediate. CN Patent 103058880 A, 2013; Chem. Abstr. 58, 650960.
3. Berg, A.; Dugstad, H.; Gacek, M.; Gulbrandsen, T.; Strande, P. Alternative dimerization reagents for synthesis of iodixanol. U.S. Patent 7,696,381 B1, 2010; Chem. Abstr. 152, 453809.
4. N-Acylation Reactions Performed in Aqueous Reaction Medium: Screening and Optimising of a Synthetic Step of a Process for Iodixanol
5. Mechanisms Of Epoxide Reactions
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