Inhibition of the Yersinia pestis Methylerythritol Phosphate Pathway of Isoprenoid Biosynthesis by α-Phenyl-Substituted Reverse Fosmidomycin Analogues

Author:

Ball Haley S.12ORCID,Girma Misgina1,Zainab Mosufa1,Riley Honoria1,Behrendt Christoph T.3,Lienau Claudia3,Konzuch Sarah3,Avelar Leandro A. A.3,Lungerich Beate3,Soojhawon Iswarduth2,Noble Schroeder M.2,Kurz Thomas3ORCID,Couch Robin D.1

Affiliation:

1. Department of Chemistry and Biochemistry, George Mason University, Manassas, Virginia 20110, United States

2. Wound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States

3. Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Universitätsstr. 1, 40225 Düsseldorf, Germany

Funder

U.S. Department of Defense

U.S. Department of Energy

Department of Chemistry and Biochemistry, George Mason University

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Reference30 articles.

1. Pneumonic Plague: The Darker Side of Yersinia pestis

2. Where Have all the Antibiotics Gone?

3. Anthrax lethal and edema toxins in anthrax pathogenesis

4. Biological and Chemical Terrorism: Strategic Plan for Preparedness and Response. Recommendations of the CDC Strategic Planning Workgroup. Morbidity and Mortality Weekly Report, 2000; Vol. 49 (RR-4), pp 1–14.

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