Synthesis of Novel Dual Target Inhibitors of CDK12 and PARP1 and Their Antitumor Activities in HER2-Positive Breast Cancers-Reference-Cited by-同舟云学术

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Synthesis of Novel Dual Target Inhibitors of CDK12 and PARP1 and Their Antitumor Activities in HER2-Positive Breast Cancers

Published:2023-07-07 Issue:28 Volume:8 Page:25574-25581
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Lin Shanshan¹²,Jiang Qingna²,Huang Xiuwang³,Xu Jianhua²^ORCID,Wu Lixian²⁴^ORCID,Liu Yang⁴⁵

Affiliation:

1. Department of Pharmacy, The Second Affiliated Hospital of Fujian Medical University, Quanzhou 362046, P. R. China

2. Department of Pharmacology, School of Pharmacy, Fujian Medical University (FMU), Fuzhou 350108, P. R. China

3. Department of Public Technology Service Center, Fujian Medical University (FMU), Fuzhou 350108, P. R. China

4. Fujian Key Laboratory of Natural Medicine Pharmacology, Fujian Medical University (FMU), Fuzhou 350108, PR China

5. Department of Medicinal Chemistry, School of Pharmacy, Fujian Medical University (FMU), Fuzhou 350108, PR China

Funder

Fujian Medical University

the Natural Science Foundation of Fujian Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.3c02912

Reference25 articles.

1. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

2. Breast cancer statistics, 2019

3. Systemic therapy for metastatic HER2-positive breast cancer

4. Local and systemic treatment for HER2-positive breast cancer with brain metastases: a comprehensive review

5. Genome profiling of ERBB2-amplified breast cancers

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2. Quinazoline-2,4(1 H,3 H)-dione Scaffold for development of a novel PARP-targeting PET probe for tumor imaging;European Journal of Nuclear Medicine and Molecular Imaging;2024-07-16

3. Quest for Discovering Novel CDK12 Inhibitor by Leveraging High-Throughput Virtual Screening;2023-09-29

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