New Pyrimidinone Bearing Aminomethylenes and Schiff Bases as Potent Antioxidant, Antibacterial, SARS-CoV-2, and COVID-19 Main Protease M<sup>Pro</sup> Inhibitors: Design, Synthesis, Bioactivities, and Computational Studies-Reference-Cited by-同舟云学术

New Pyrimidinone Bearing Aminomethylenes and Schiff Bases as Potent Antioxidant, Antibacterial, SARS-CoV-2, and COVID-19 Main Protease M^Pro Inhibitors: Design, Synthesis, Bioactivities, and Computational Studies

Published:2024-06-04 Issue:24 Volume:9 Page:25730-25747
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Sarfraz Muhammad¹,Ayyaz Muhammad¹,Rauf Abdul¹,Yaqoob Asma²,Tooba ²,Arif Ali Muhammad¹,Siddique Sabir Ali¹,Qureshi Ashfaq Mahmood³,Sarfraz Muhammad Hassan⁴^ORCID,Aljowaie Reem M.⁵,Almutairi Saeedah Musaed⁵,Arshad Muhammad¹^ORCID

Affiliation:

1. Institute of Chemistry, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan

2. Institute of Biochemistry, Biotechnology, and Bioinformatics. Department of Biochemistry and Molecular Biology, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan

3. Department of Chemistry, Government Sadiq College Women University, Bahawalpur 63100, Pakistan

4. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Institute of Musculoskeletal Sciences, University of Oxford, OxfordOX3 7LD, United Kingdom

5. Department of Botany and Microbiology, College of Science, King Saud University, P O 2455 Riyadh 11451, Saudi Arabia

Funder

King Saud University

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.3c09393

Reference65 articles.

1. Pyrimidine: An elite heterocyclic leitmotif in drug discovery‐synthesis and biological activity

2. Significance and Biological Importance of Pyrimidine in the Microbial World

3. Antiviral Activity of Pyrimidine Containing Compounds: Patent Review

4. Novel Pyrimidine Derivatives as Potential Anticancer Agents: Synthesis, Biological Evaluation and Molecular Docking Study

5. Recent Development of Pyrimidine‐Containing Antimicrobial Agents

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