Investigating Paracetamol’s Role as a Potential Treatment for Parkinson’s Disease: Ab Initio Analysis of Dopamine, l-DOPA, Paracetamol, and NAPQI Interactions with Enzymes Involved in Dopamine Metabolism
Author:
Affiliation:
1. School of Chemistry Food and Pharmacy, University of Reading, Reading RG6 6AD, U.K.
2. School of Sciences, University of Wolverhampton, Wolverhampton WV1 1LY, U.K.
Funder
Royal Society of Chemistry
Publisher
American Chemical Society (ACS)
Subject
General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsomega.3c03888
Reference41 articles.
1. Molecular Effects of L-dopa Therapy in Parkinson’s Disease
2. A comprehensive review on management of Parkinson’s disease, inclusive of drug discovery and pharmacological approaches
3. Tyrosinase inhibition by some flavonoids: Inhibitory activity, mechanism by in vitro and in silico studies
4. The Role of Paracetamol (acetaminophen) in the Reduction of Tremor in Parkinson’s Disease – a Case Study
5. Mechanistic insights into the protective effect of paracetamol against rotenone-induced Parkinson’s disease in rats: Possible role of endocannabinoid system modulation
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2. Pairwise Additivity and Three-Body Contributions for Density Functional Theory-Based Protein–Ligand Interaction Energies;The Journal of Physical Chemistry B;2024-02-29
3. Exploring acetaminophen prodrugs and hybrids: a review;RSC Advances;2024
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