Cyclization of Chalcone Derivatives: Design, Synthesis, <i>In Silico</i> Docking Study, and Biological Evaluation of New Quinazolin-2,4-diones Incorporating Five-, Six-, and Seven-Membered Ring Moieties as Potent Antibacterial Inhibitors-Reference-Cited by-同舟云学术

Cyclization of Chalcone Derivatives: Design, Synthesis, In Silico Docking Study, and Biological Evaluation of New Quinazolin-2,4-diones Incorporating Five-, Six-, and Seven-Membered Ring Moieties as Potent Antibacterial Inhibitors

Published:2023-07-21 Issue:30 Volume:8 Page:27216-27230
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

El-Naggar Mohamed¹²,Rashdan Huda R. M.³^ORCID,Abdelmonsef Aboubakr H.⁴^ORCID

Affiliation:

1. Chemistry Department, Pure and Applied Chemistry Group, Faculty of Sciences, University of Sharjah, Sharjah 27272, UAE

2. National Institute of Oceanography and Fisheries, Kayak Bay, Alexandria 21556, Egypt

3. Chemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre, Dokki, Cairo 12622, Egypt

4. Chemistry Department, Faculty of Science, South Valley University, Qena 83523, Egypt

Funder

South Valley University

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.3c02478

Reference31 articles.

1. Antimicrobial resistance: A global emerging threat to public health systems

2. A search for antiinflammatory therapies: Synthesis, in silico investigation of the mode of action, and in vitro analyses of new quinazolin‐2,4‐dione derivatives targeting phosphodiesterase‐4 enzyme