Development of New Leishmanicidal Compounds via Bioconjugation of Antimicrobial Peptides and Antileishmanial Guanidines

Author:

Costa Natalia C. S.1,dos Anjos Luana Ribeiro2,de Souza João Victor Marcelino1,Brasil Maria Carolina Oliveira de Arruda1,Moreira Vitor Partite2,Graminha Marcia A. S.3ORCID,Lubec Gert4ORCID,Gonzalez Eduardo Rene P.2ORCID,Cilli Eduardo Maffud1ORCID

Affiliation:

1. Department of Biochemistry and Organic Chemistry, Institute of Chemistry, São Paulo State University (UNESP), 14800-060 Araraquara, São Paulo, Brazil

2. Fine Organic Chemistry Lab, School of Sciences and Technology, São Paulo State University (UNESP), 19060-080 Presidente Prudente, Sao Paulo, Brazil

3. School of Pharmaceutical Sciences, São Paulo State University (UNESP), 14800-903 Araraquara, São Paulo, Brazil

4. Department of Neuroproteomics, Paracelsus Medical University, 5020 Salzburg, Austria

Funder

Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico

Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo

Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Reference60 articles.

1. Maia-Elkhoury, A. N. S.; Rocha, S. Y. O. V.; Buzanovsky, L. P.; Sanchez-Vazquez, D. M. L. M. J. Leishmanioses: Informe epidemiológico das Américas. No 11 (Dezembro de 2022); OPS/CDE/VT/22–0021: Organización Panamericana de la Salud, 2022; https://iris.paho.org/handle/10665.2/56832.

2. Leishmaniasis treatment update of possibilities for drug repurposing

3. Drug repurposing and human parasitic protozoan diseases

4. Antimicrobial Peptides—Mechanisms of Action, Antimicrobial Effects and Clinical Applications

5. Advances and perspectives for antimicrobial peptide and combinatory therapies

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