Development of an RHEB-Targeting Peptide To Inhibit mTORC1 Kinase Activity-Reference-Cited by-同舟云学术

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Development of an RHEB-Targeting Peptide To Inhibit mTORC1 Kinase Activity

Published:2022-06-24 Issue:27 Volume:7 Page:23479-23486
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Shams Raef¹²^ORCID,Ito Yoshihiro¹³^ORCID,Miyatake Hideyuki²³^ORCID

Affiliation:

1. Emergent Bioengineering Materials Research Team, RIKEN Center for Emergent Matter Science, Wako, Saitama 351-0198, Japan

2. Department of Life Science, Graduate School of Science and Engineering, Saitama University, Saitama City, Saitama 338-8570, Japan

3. Nano Medical Engineering Laboratory, RIKEN Cluster for Pioneering Research, Wako, Saitama 351-0198, Japan

Funder

RIKEN

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.2c01865

Reference33 articles.

1. Mapping of mTOR drug targets: Featured platforms for anti-cancer drug discovery

2. mTOR at the nexus of nutrition, growth, ageing and disease

3. Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40

4. mTOR kinase structure, mechanism and regulation

5. mTOR signalling and cellular metabolism are mutual determinants in cancer

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