Altering the Regioselectivity of Cytochrome P450 BM3 Variant M13 toward Genistein through Protein Engineering and Variation of Reaction Conditions-Reference-Cited by-同舟云学术

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Altering the Regioselectivity of Cytochrome P450 BM3 Variant M13 toward Genistein through Protein Engineering and Variation of Reaction Conditions

Published:2020-12-02 Issue:49 Volume:5 Page:32059-32066
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Hong Li-Li¹,Kong Jian-Qiang¹^ORCID

Affiliation:

1. Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College (State Key Laboratory of Bioactive Substance and Function of Natural Medicines & NHC Key Laboratory of Biosynthesis of Natural Products), Beijing 100050, China

Funder

Peking Union Medical College

Chinese Academy of Medical Sciences

National Mega-project for Innovative Drugs

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acsomega.0c05088

Reference39 articles.

1. Understanding genistein in cancer: The “good” and the “bad” effects: A review

2. Anti-inflammatory, anti-osteoclastic, and antioxidant activities of genistein protect against alveolar bone loss and periodontal tissue degradation in a mouse model of periodontitis

3. Hypotensive effects of genistein: From chemistry to medicine

4. Microbial Hydroxylation and Methylation of Genistein by Streptomycetes

5. High production of genistein diglucoside derivative using cyclodextrin glycosyltransferase from Paenibacillus macerans

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1. Rational Design of the Spatial Effect in a Fe(II)/α‐Ketoglutarate‐Dependent Dioxygenase Reverses the Regioselectivity of C(sp³)−H Bond Hydroxylation in Aliphatic Amino Acids;Angewandte Chemie International Edition;2024-07-03

2. Rational Design of the Spatial Effect in a Fe(II)/α‐Ketoglutarate‐Dependent Dioxygenase Reverses the Regioselectivity of C(sp³)−H Bond Hydroxylation in Aliphatic Amino Acids;Angewandte Chemie;2024-07-03

3. A promiscuous xyloglucan xylosyltransferase 1 (OsaXXT1) from Ornithogalum saundersiae recognizes both cello-oligosaccharides and nonsaccharide lignans;Journal of Molecular Structure;2024-04

4. Biosynthesis of eriodictyol in citrus waster by endowing P450BM3 activity of naringenin hydroxylation;Applied Microbiology and Biotechnology;2024-01-08

5. Exploring 3-O-glycosylations of 20(R)-dammarane ginsenosides and the catalytic mechanism underlying the stereoselectivity with the combined assistance of AlphaFold 2 and molecular docking;International Journal of Biological Macromolecules;2024-01

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