Synthesis of Triphenylphosphonium-Linked Derivative of 3,5-Di<i>tert</i>-butyl-4-hydroxybenzylidene-malononitrile (SF6847) via Knoevenagel Reaction Yields an Effective Mitochondria-Targeted Protonophoric Uncoupler-Reference-Cited by-同舟云学术

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Synthesis of Triphenylphosphonium-Linked Derivative of 3,5-Ditert-butyl-4-hydroxybenzylidene-malononitrile (SF6847) via Knoevenagel Reaction Yields an Effective Mitochondria-Targeted Protonophoric Uncoupler

Published:2024-02-29 Issue:10 Volume:9 Page:11551-11561
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Kirsanov Roman S.¹,Khailova Ljudmila S.¹,Rokitskaya Tatyana I.¹^ORCID,Lyamzaev Konstantin G.¹²,Panteleeva Alisa A.¹,Nazarov Pavel A.¹^ORCID,Firsov Alexander M.¹,Iaubasarova Iliuza R.¹,Korshunova Galina A.¹,Kotova Elena A.¹,Antonenko Yuri N.¹^ORCID

Affiliation:

1. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia

2. The “Russian Clinical Research Center for Gerontology” of the Ministry of Healthcare of the Russian Federation, Pirogov Russian National Research Medical University, 117997 Moscow, Russia

Funder

Russian Science Foundation

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.3c08621

Reference71 articles.

1. Actions of Dinitrophenol

2. REVERSIBLE INHIBITION OF THE COUPLING BETWEEN PHOSPHORYLATION AND OXIDATION

3. DINITROPHENOL IN THE TREATMENT OF OBESITY

4. Therapeutic potential of mitochondrial uncouplers for the treatment of metabolic associated fatty liver disease and NASH

5. Exploring the therapeutic potential of mitochondrial uncouplers in cancer

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