Peptide Conjugates of a 2′-<i>O</i>-Methoxyethyl Phosphorothioate Splice-Switching Oligonucleotide Show Increased Entrapment in Endosomes-Reference-Cited by-同舟云学术

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Peptide Conjugates of a 2′-O-Methoxyethyl Phosphorothioate Splice-Switching Oligonucleotide Show Increased Entrapment in Endosomes

Published:2023-10-17 Issue:43 Volume:8 Page:40463-40481
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Hill Alyssa C.¹^ORCID,Becker J. Philipp¹^ORCID,Slominski Daria¹,Halloy François¹,Søndergaard Christoffer²,Ravn Jacob²,Hall Jonathan¹^ORCID

Affiliation:

1. Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, Eidgenössische Technische Hochschule Zürich (ETH Zürich), Zürich 8093, Switzerland

2. Roche Innovation Center Copenhagen (RICC), Hørsholm 2970, Denmark

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Roche Innovation Center Copenhagen

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.3c05144

Reference107 articles.

1. Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide.

2. RNA-Targeted Therapeutics

3. Delivery of oligonucleotide‐based therapeutics: challenges and opportunities

4. Challenges and Opportunities for Nucleic Acid Therapeutics

5. The delivery of therapeutic oligonucleotides

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