Pharmacophore Virtual Screening Identifies Riboflavin as an Inhibitor of the Schistosome Cathepsin B1 Protease with Antiparasitic Activity-Reference-Cited by-同舟云学术

Pharmacophore Virtual Screening Identifies Riboflavin as an Inhibitor of the Schistosome Cathepsin B1 Protease with Antiparasitic Activity

Published:2024-05-30 Issue:23 Volume:9 Page:25356-25369
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Cogo Ramon M.¹^ORCID,Pavani Thaís F. A.¹,Mengarda Ana C. A.²,Cajas Rayssa A.²,Teixeira Thainá R.²,Fukui-Silva Lucas²,Sun Yujie Uli³,Liu Lawrence J.³^ORCID,Amarasinghe Dilini K.³,Yoon Michael C.³^ORCID,Santos-Filho Osvaldo A.⁴^ORCID,de Moraes Josué²^ORCID,Caffrey Conor R.³,G. G. Rando Daniela⁵^ORCID

Affiliation:

1. Universidade Federal de São Paulo─Campus Diadema, Curso de Pós-Graduação em Biologia Química da Unifesp, Rua São Nicolau 210, 2o andar, Centro, Diadema, São Paulo 09972-270, Brazil

2. Universidade Guarulhos, Núcleo de Pesquisa em Doenças Negligenciadas─NPDN, Praça Tereza Cristina 88, Guarulhos 09972-270, Brazil

3. Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093-0021, United States

4. Instituto de Pesquisas de Produtos Naturais Walter Mors, Universidade Federal do Rio de Janeiro, Av. Carlos Chagas Filho, 373, Bloco H, Rio de Janeiro 21941-853, Brazil

5. Grupo de Pesquisas Químico-Farmacêuticas da Unifesp, Department of Pharmaceutical Sciences Rua São Nicolau, Universidade Federal de São Paulo─Campus Diadema, 210, 2o andar, Centro, Diadema, São Paulo 09972-270, Brazil

Funder

National Institute of Allergy and Infectious Diseases

Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico

Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo

Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.4c03376

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