Enantiomeric Separation, Absolute Configuration by X-ray Crystallographic Analysis, and Functional Evaluation of Enantiomers of the Dual Ligand, SYA0340 at 5-HT<sub>1A</sub> and 5-HT<sub>7A</sub> Receptors-Reference-Cited by-同舟云学术

Enantiomeric Separation, Absolute Configuration by X-ray Crystallographic Analysis, and Functional Evaluation of Enantiomers of the Dual Ligand, SYA0340 at 5-HT_1A and 5-HT_7A Receptors

Published:2023-06-07 Issue:24 Volume:8 Page:21736-21744
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Bricker Barbara A.¹,Voshavar Chandrashekhar¹,Onyameh Edem K.¹,Gonela Uma M.¹,Lin Xinsong²,Swanson Tracy L.³,Kozell Laura B.³,Schmachtenberg Jennifer L.³,Bloom Shelley H.³,Janowsky Aaron J.³,Ablordeppey Seth Y.¹^ORCID

Affiliation:

1. Division of Basic Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health, Florida A&M University, Tallahassee, Florida 32307, United States

2. Department of Chemistry and Biochemistry, Florida State University, 95 Chieftan Way Room 118 DLC, Tallahassee, Florida 32306-4390, United States

3. Research Service, VA Portland Health Care System, and Department of Psychiatry, Oregon Health and Science University, Portland Oregon 97239, United States

Funder

U.S. Department of Education

National Institute on Minority Health and Health Disparities

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.3c01283

Reference27 articles.

1. International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function

2. 5-HT1A gene variants and psychiatric disorders: a review of current literature and selection of SNPs for future studies

3. Biased agonism at serotonin 5-HT1Areceptors: preferential postsynaptic activity for improved therapy of CNS disorders

4. 5-HT1A receptors are differentially involved in the anxiolytic- and antidepressant-like effects of 8-OH-DPAT and fluoxetine in the rat

5. The Serotonin-1A Receptor in Anxiety Disorders

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