Linagliptin and Empagliflozin Inhibit Microtubule Affinity Regulatory Kinase 4: Repurposing Anti-Diabetic Drugs in Neurodegenerative Disorders Using In Silico and In Vitro Approaches-Reference-Cited by-同舟云学术

Linagliptin and Empagliflozin Inhibit Microtubule Affinity Regulatory Kinase 4: Repurposing Anti-Diabetic Drugs in Neurodegenerative Disorders Using In Silico and In Vitro Approaches

Published:2023-02-07 Issue:7 Volume:8 Page:6423-6430
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Atiya Akhtar¹,Das Gupta Debarati²^ORCID,Alsayari Abdulrhman¹³,Alrouji Mohammed⁴,Alotaibi Abdulmajeed⁵,Sharaf Sharaf E.⁶,Abdulmonem Waleed Al⁷,Alorfi Nasser M.⁸,Abdullah K. M.⁹,Shamsi Anas¹⁰^ORCID

Affiliation:

1. Department of Pharmacognosy, College of Pharmacy, King Khalid University (KKU), Guraiger St., Abha 62529, Saudi Arabia

2. College of Pharmacy, University of Michigan, 2428 Church Street, Ann Arbor, Michigan 48109, United States

3. Complementary and Alternative Medicine Unit, King Khalid University (KKU), Guraiger St., Abha 62529, Saudi Arabia

4. Department of Medical Laboratories, College of Applied Medical Sciences, Shaqra University, Shaqra 11961, Saudi Arabia

5. College of Applied Medical Sciences, King Saud bin Abdulaziz University for Health Sciences, Riyadh 11426, Saudi Arabia

6. Pharmaceutical Chemistry Department, College of Pharmacy, Umm Al-Qura University, Makkah 21421, Saudi Arabia.

7. Department of Pathology, College of Medicine, Qassim University, Buraydah 52571, Saudi Arabia

8. Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah 21421, Saudi Arabia

9. Department of Biochemistry, Jain University, Bengaluru 560069, India

10. Centre of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman 346, United Arab Emirates

Funder

Shaqra University

Ajman University

King Khalid University

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.2c06634

Reference43 articles.

1. Computational Drug Repurposing for Alzheimer’s Disease Using Risk Genes From GWAS and Single-Cell RNA Sequencing Studies

2. Inhibition of PDK3 by artemisinin, a repurposed antimalarial drug in cancer therapy

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5. Drug Repositioning for Alzheimer’s Disease Based on Systematic ‘omics’ Data Mining

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