Exploring the Potential of New Benzamide-Acetamide Pharmacophore Containing Sulfonamide as Urease Inhibitors: Structure–Activity Relationship, Kinetics Mechanism, and In Silico Studies-Reference-Cited by-同舟云学术

Exploring the Potential of New Benzamide-Acetamide Pharmacophore Containing Sulfonamide as Urease Inhibitors: Structure–Activity Relationship, Kinetics Mechanism, and In Silico Studies

Published:2023-11-22 Issue:48 Volume:8 Page:46165-46181
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Ahmad Saghir¹²,Abdul Qadir Muhammad¹,Ahmed Mahmood³^ORCID,Imran Muhammad⁴,Ahmad Muhammad³,Yousaf Numan⁵,Wani Tanveer A.⁶^ORCID,Zargar Seema⁷^ORCID,Ali Ijaz⁸,Muddassar Muhammad⁵

Affiliation:

1. School of Chemistry, University of the Punjab, Lahore 54590, Pakistan

2. Department of Microbiology, Immunology and Cancer Biology, School of Medicine, University of Virginia, Charlottesville, Virginia 22903, United States

3. Department of Chemistry, Division of Science and Technology, University of Education, College Road, Lahore 54770, Pakistan

4. KAM School of Life Sciences, FC College (A Chartered University), Lahore 54600, Pakistan

5. Department of Biosciences, COMSATS University Islamabad, Park Road, Islamabad 45550, Pakistan

6. Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia

7. Department of Biochemistry, College of Science, King Saud University, P.O. Box 222452, Riyadh 11451, Saudi Arabia

8. Centre for Applied Mathematics and Bioinformatics (CAMB), Gulf University for Science and Technology, Hawally 32093, Kuwait

Funder

Higher Education Commission, Pakistan

King Saud University

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.3c07275

Reference42 articles.

1. A novel series of thiosemicarbazone hybrid scaffolds: Design, synthesis, DFT studies, metabolic enzyme inhibition properties, and molecular docking calculations

2. An Understanding of Mechanism-Based Approaches for 1,3,4-Oxadiazole Scaffolds as Cytotoxic Agents and Enzyme Inhibitors

3. Discovery and biosynthesis of karnamicins as angiotensin converting enzyme inhibitors

4. Biology-oriented drug synthesis (BIODS), in vitro urease inhibitory activity, and in silico study of S-naproxen derivatives

5. Levofloxacin and sulfa drugs linked via Schiff bases: Exploring their urease inhibition, enzyme kinetics and in silico studies

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