Design, Synthesis, and Bioevaluation of Indole Core Containing 2-Arylidine Derivatives of Thiazolopyrimidine as Multitarget Inhibitors of Cholinesterases and Monoamine Oxidase A/B for the Treatment of Alzheimer Disease-Reference-Cited by-同舟云学术

Design, Synthesis, and Bioevaluation of Indole Core Containing 2-Arylidine Derivatives of Thiazolopyrimidine as Multitarget Inhibitors of Cholinesterases and Monoamine Oxidase A/B for the Treatment of Alzheimer Disease

Published:2022-03-10 Issue:11 Volume:7 Page:9369-9379
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Shahid Nadeem Muhammad¹,Azam Khan Jalaluddin¹,Kazmi Imran¹,Rashid Umer²^ORCID

Affiliation:

1. Department of Biochemistry, Faculty of Science, King Abdulaziz University Jeddah, 21589, Saudi Arabia

2. Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad, 22060, Pakistan

Funder

King Abdulaziz University

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.1c06344

Reference47 articles.

1. Challenges in Designing Therapeutic Agents for Treating Alzheimer’s Disease-from Serendipity to Rationality

2. Multi-target-Directed Ligands To Combat Neurodegenerative Diseases

3. Donepezil–tacrine hybrid related derivatives as new dual binding site inhibitors of AChE

4. Global Trends in Alzheimer Disease Clinical Development: Increasing the Probability of Success

5. Current and novel therapeutic molecules and targets in Alzheimer's disease

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