In Silico and Structure-Based Assessment of Similar Variants Discovered in Tandem Repeats of BRCT Domains of BRCA1 and BARD1 To Characterize the Folding Pattern

Author:

Barua Siddhartha A.12,Goswami Nabajyoti1ORCID,Mishra Neha12,Sawant Ulka U.1,Varma Ashok K.12ORCID

Affiliation:

1. Advanced Centre for Treatment, Research and Education in Cancer, Kharghar, Navi Mumbai, Maharashtra 410210, India

2. Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai, Maharashtra 400094, India

Funder

Department of Biotechnology , Ministry of Science and Technology

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Reference57 articles.

1. Cancer statistics for the year 2020: An overview

2. Centres for Disease Control and Prevention (the CDC, USA). Centres for Disease Control and Prevention (2021).

3. BRCA1 and BRCA2: different roles in a common pathway of genome protection

4. The BRCT Domain Is a Phospho-Protein Binding Domain

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