Molecular Dynamics-Based Design and Biophysical Evaluation of Thermostable Single-Chain Fv Antibody Mutants Derived from Pharmaceutical Antibodies-Reference-Cited by-同舟云学术

Molecular Dynamics-Based Design and Biophysical Evaluation of Thermostable Single-Chain Fv Antibody Mutants Derived from Pharmaceutical Antibodies

Published:2023-06-09 Issue:25 Volume:8 Page:22945-22954
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Okazaki Kyo¹,Kobashigawa Yoshihiro¹,Morita Hikari¹,Yamauchi Soichiro¹,Fukuda Natsuki¹,Liu Chenjiang¹,Toyota Yuya¹,Sato Takashi¹,Morioka Hiroshi¹^ORCID

Affiliation:

1. Department of Analytical and Biophysical Chemistry, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan

Funder

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.3c01948

Reference50 articles.

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4. Tailoring in vitro evolution for protein affinity or stability

5. [34] Expression of functional antibody Fv and Fab fragments in Escherichia coli

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