Encapsulation of Chemotherapeutic Drug Melphalan in Cucurbit[7]uril: Effects on Its Alkylating Activity, Hydrolysis, and Cytotoxicity
Author:
Affiliation:
1. Laboratorio de Química Biosupramolecular, Departamento de Química Física, Facultad de Química, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile
Funder
Comisión Nacional de Investigación Científica y Tecnológica
Fondo Nacional de Desarrollo Científico y Tecnológico
Publisher
American Chemical Society (ACS)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.acs.org/doi/pdf/10.1021/acsomega.8b01335
Reference44 articles.
1. Melphalan and its role in the management of patients with multiple myeloma
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4. DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards is preserved in intact cells
5. The Mechanism of Guanine Alkylation by Nitrogen Mustards: A Computational Study
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