Synthesis, Characterization, and In Vivo Evaluation of Desmethyl Anethole Trithione Phosphate Prodrug for Ameliorating Cerebral Ischemia-Reperfusion Injury in Rats-Reference-Cited by-同舟云学术

Synthesis, Characterization, and In Vivo Evaluation of Desmethyl Anethole Trithione Phosphate Prodrug for Ameliorating Cerebral Ischemia-Reperfusion Injury in Rats

Published:2020-02-24 Issue:9 Volume:5 Page:4595-4602
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Huang Sheng¹,Dong Renhan¹²,Xu Gaojie¹,Liu Jin¹,Gao Xiaofang¹,Yu Siqi¹,Qie Pengfan¹,Gou Gang¹,Hu Min¹,Wang Yu¹,Peng Jian¹,Guang Bing¹²,Xu Ying³,Yang Tai¹^ORCID

Affiliation:

1. School of Pharmacy, Chengdu Medical College, No. 783, Xindu Avenue, Xindu District, Chengdu 610500, Sichuan, China

2. Chengdu Beinuokecheng Biotechnology Co., Ltd., No. 88, Keyuan South Road, New and High-Tech Zone, Chengdu 610094, Sichuan, China

3. The First Affiliated Hospital, Chengdu Medical College, Chengdu 610500, Sichuan, China

Funder

Chengdu Science and Technology Bureau

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acsomega.9b04129

Reference33 articles.

1. Hydrogen Sulfide-Releasing Therapeutics: Translation to the Clinic

2. Treatment of Xerostomia with the Bile Secretion-Stimulating Drug Anethole Trithione: A Clinical Trial

3. Metabolism of Anethole Dithiolethione by Rat and Human Liver Microsomes: Formation of Various Products Deriving from Its O-Demethylation and S-Oxidation. Involvement of Cytochromes P450 and Flavin Monooxygenases in These Pathways

4. Chemopreventive efficacy of anethole trithione, N-acetyl-L-cysteine, miconazole and phenethylisothiocyanate in the DMBA-induced rat mammary cancer model

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