Intrinsic Proteolytic Activities from Cancer Cells Are Sufficient to Activate Alkoxyamine Prodrugs and Induce Cell Death
Author:
Affiliation:
1. Aix-Marseille University, CNRS, UMR 7273, Marseille 13007, France
2. Magnetic Resonance of Biological Systems, UMR 5536 CNRS-University of Bordeaux, Bordeaux 33076, France
3. INSERM, Bordeaux 33076, France
Funder
H2020 Future and Emerging Technologies
Publisher
American Chemical Society (ACS)
Link
https://pubs.acs.org/doi/pdf/10.1021/acsomega.4c05592
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1. Protease-Activated Drug Development
2. Enzyme-activated prodrugs and their release mechanisms for the treatment of cancer
3. A β-glucuronidase-responsive albumin-binding prodrug programmed for the double release of monomethyl auristatin E
4. The First Generation of β-Galactosidase-Responsive Prodrugs Designed for the Selective Treatment of Solid Tumors in Prodrug Monotherapy
5. Glycosidase activated prodrugs for targeted cancer therapy
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