Synthesis and Biological Evaluation of Lysophosphatidic Acid Analogues Using Conformational Restriction and Bioisosteric Replacement Strategies
Author:
Affiliation:
1. Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aza-aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan
2. Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
Funder
Ministry of Education, Culture, Sports, Science and Technology
Moonshot Research and Development Program
Japan Society for the Promotion of Science
Publisher
American Chemical Society (ACS)
Subject
General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsomega.3c07668
Reference45 articles.
1. Lysophospholipid receptor nomenclature review: IUPHAR Review 8
2. Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors
3. Role of lysophosphatidic acid and its receptors in health and disease: novel therapeutic strategies
4. Lysophosphatidic acid (LPA) signalling in cell migration and cancer invasion: A focussed review and analysis of LPA receptor gene expression on the basis of more than 1700 cancer microarrays
5. Lysophosphatidic Acid Stimulates the Proliferation of Ovarian Cancer Cells via the gep Proto-Oncogene G 12
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