Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis

Author:

Herrera Natalia G.1ORCID,Morano Nicholas C.1,Celikgil Alev1,Georgiev George I.1,Malonis Ryan J.1,Lee James H.1,Tong Karen1,Vergnolle Olivia1,Massimi Aldo B.1,Yen Laura Y.2,Noble Alex J.2,Kopylov Mykhailo2,Bonanno Jeffrey B.1,Garrett-Thomson Sarah C.1,Hayes David B.3,Bortz Robert H.4,Wirchnianski Ariel S.14,Florez Catalina45,Laudermilch Ethan4,Haslwanter Denise4,Fels J. Maximilian4,Dieterle M. Eugenia4,Jangra Rohit K.4,Barnhill Jason5,Mengotto Amanda6,Kimmel Duncan6,Daily Johanna P.46,Pirofski Liise-anne46,Chandran Kartik4,Brenowitz Michael1,Garforth Scott J.1,Eng Edward T.2,Lai Jonathan R.1ORCID,Almo Steven C.1

Affiliation:

1. Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Ave., Bronx, New York 10461, United States

2. National Resource for Molecular Microscopy, Simons Electron Microscopy Center, New York Structural Biology Center, 89 Convent Ave., New York, New York 10027, United States

3. International Solidarity of Scientists LLC, 9 Chuck Wagon Lane, Danbury, Connecticut 06810, United States

4. Department of Microbiology and Immunology, Albert Einstein College of Medicine, 1300 Morris Park Ave., Bronx, New York 10461, United States

5. Department of Chemistry and Life Science, United States Military Academy at West Point, 646 Swift Road, West Point, New York 10996, United States

6. Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, New York, New York 10461, United States

Funder

National Cancer Institute

National Institute of Allergy and Infectious Diseases

G. Harold and Leila Y. Mathers Charitable Foundation

Pew Charitable Trusts

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

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