Development of an Absolute Quantification Method for hERG Using PRM with Single Isotopologue in-Sample Calibration-Reference-Cited by-同舟云学术

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Development of an Absolute Quantification Method for hERG Using PRM with Single Isotopologue in-Sample Calibration

Published:2024-07-25 Issue:31 Volume:9 Page:33972-33982
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Chang Ge¹,Aroge Fabusuyi A.²,Venkateshappa Ravichandra³,Claydon Tom W.³,Sun Bingyun¹^ORCID

Affiliation:

1. Department of Chemistry, Simon Fraser University, Burnaby, British Columbia V5A1S6, Canada

2. School of Mechatronic Systems Engineering, Simon Fraser University, Surrey, British Columbia V3T0A3, Canada

3. Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia V5A1S6, Canada

Funder

Canadian Institutes of Health Research

Canada Foundation for Innovation

Compute Canada

Natural Sciences and Engineering Research Council of Canada

British Columbia Knowledge Development Fund

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.4c04541

Reference58 articles.

1. hERG quality control and the long QT syndrome

2. International Union of Pharmacology. XLI. Compendium of Voltage-Gated Ion Channels: Potassium Channels

3. hERG K+Channels: Structure, Function, and Clinical Significance

4. The inward rectification mechanism of the HERG cardiac potassium channel

5. A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

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