Efficient Synthesis of a Chiral Precursor for Angiotensin-Converting Enzyme (ACE) Inhibitors in High Space-Time Yield by a New Reductase without External Cofactors-Reference-Cited by-同舟云学术

Efficient Synthesis of a Chiral Precursor for Angiotensin-Converting Enzyme (ACE) Inhibitors in High Space-Time Yield by a New Reductase without External Cofactors

Published:2012-04-05 Issue:8 Volume:14 Page:1982-1985
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Shen Nai-Dong¹,Ni Yan¹,Ma Hong-Min¹,Wang Li-Juan¹,Li Chun-Xiu¹,Zheng Gao-Wei¹,Zhang Jie¹,Xu Jian-He¹

Affiliation:

1. Laboratory of Biocatalysis and Synthetic Biotechnology, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, People’s Republic of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol300397d

Reference32 articles.

1. Towards a Large-Scale Asymmetric Reduction Process with Isolated Enzymes: Expression of an (S)-Alcohol Dehydrogenase in E.coli and Studies on the Synthetic Potential of this Biocatalyst

2. Practical chiral alcohol manufacture using ketoreductases

3. Isolation of a Bacillus strain producing ketone reductase with high substrate tolerance

4. Enantioselective reductions of ethyl 2-oxo-4-phenylbutyrate by Saccharomyces cerevisiae dehydrogenases

5. Preparation the Key Intermediate of Angiotensin-Converting Enzyme (ACE) Inhibitors: High Enantioselective Production of Ethyl (R)-2-Hydroxy-4-Phenylbutyrate withCandida boidinii CIOC21

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