Synthesis of Novel Diarylpyrimidine Analogues and Their Antiviral Activity against Human Immunodeficiency Virus Type 1-Reference-Cited by-同舟云学术

Synthesis of Novel Diarylpyrimidine Analogues and Their Antiviral Activity against Human Immunodeficiency Virus Type 1

Published:2004-11-18 Issue:6 Volume:48 Page:2072-2079
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Guillemont Jerome¹,Pasquier Elisabeth¹,Palandjian Patrice¹,Vernier Daniel¹,Gaurrand Sandrine¹,Lewi Paul J.¹,Heeres Jan¹,de Jonge Marc R.¹,Koymans Lucien M. H.¹,Daeyaert Frits F. D.¹,Vinkers Maarten H.¹,Arnold Eddy¹,Das Kalyan¹,Pauwels Rudi¹,Andries Koen¹,de Béthune Marie-Pierre¹,Bettens Eva¹,Hertogs Kurt¹,Wigerinck Piet¹,Timmerman Philip¹,Janssen Paul A. J.¹

Affiliation:

1. Medicinal Chemistry Department, Johnson & Johnson Pharmaceutical Research and Development, Campus de Maigremont BP615, Val de Reuil, France, Center for Molecular Design, Janssen Pharmaceutica NV, Vosselaar, Belgium, Tibotec, General De Wittelaan L11B3, B-2800 Mechelen, Belgium, Pharmacokinetic Department, Johnson & Johnson Pharmaceutical Research and Development, Tumhoutseweg 30 B-2340 Beerse, Belgium, and Center for Advanced Biotechnology and Medicine, Chemistry Department, Rutgers University, 679 Hoes...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm040838n

Reference19 articles.

1. Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs): Past, Present, and Future

2. Multiple Mutations in HIV-1 Reverse Transcriptase Confer High-Level Resistance to Zidovudine (AZT)

3. HIV with Reduced Sensitivity to Zidovudine (AZT) Isolated During Prolonged Therapy

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